CANNASPORT RESEARCH has been involved in the research of plant substances and their use in competitive sports for many years. CANNASPORT RESEARCH - that means more than 20 years of experience in the development of sports supplements and a worldwide network of experts from which companies and athletes benefit! The research of the human cannabinoid system and the sensible use of cannabidiol (CBD) in sports is our mission statement, which we have dedicated ourselves to. 

What is CBD and the endocannabinoid system?


Cannabidiol, or CBD for short, is the non-psychoactive cannabinoid from the hemp plant. Cannabidiol is classified as a so-called cannabinoid. Cannabinoids are active substances which were mainly found in the hemp plant (Cannabis sativa or Cannabis indica). The best known cannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC). The latter is responsible for the intoxicating effects of hemp plants. In comparison to many other plant active substances, cannabinoids were researched relatively late. It was not until the 1970s that researchers succeeded in deciphering the structure of cannabidiol and THC. During these investigations, they discovered a previously unknown area in our body: the endocannabinoid system. This system, also called "ECS" for short, is the key to successful use in sport!


There are two different types of cannabinoids that can be useful to the human body - exogenous (externally supplied) and endogenous (produced by the body itself) cannabinoids. Both can activate the receptors of the ECS (endocannabinoid system).

Synthetic Cannabinoids (Exogenous)

Cannabinoid mimetics (synthetic cannabinoids) are molecules that produce pharmacological effects in the human body similar to those of 

cannabinoids, but are produced artificially and are not taken from the cannabis plant. Known compounds are e.g. JWH-018, AM-1220 and UR-144.

Phytocannabinoids (exogenous)

Phytocannabinoids are plant cannabinoids, which are mainly derived from the hemp plant. Other specific plants may also contain cannabinoids, but the hemp plant is by far the most potent. The two best known cannabinoids are THC (tetrahydrocannabinol) and CBD (cannabidiol).

Endocannabinoids (endogenous)

Endocannabinoids are so-called endogenous cannabinoids and are produced naturally in the body. They dock to the receptors of the cannabinoid system in the same way as cannabinoids that are fed from the outside.


Synthetic cannabinoids (also known as cannabimimetica) are various chemically synthesized compounds that usually have a similar effect to tetrahydrocannabinol (THC), the psychoactive agent of cannabis sativa. Well-known compounds include JWH-018, AM-1220 and UR-144, which are present in crystalline, powdery or liquid form or may be present as synthetic additives in alleged "herbal" or "incense mixtures".  Classic synthetic cannabinoids are those artificial variations of the basic cannabinoid molecule structure that have retained the natural cannabinoid ring structure and its oxygen atoms.


Non-classical cannabinoids are molecules that have undergone a more pronounced change in their original structures or the isosteric exchange of an atom. This often happens together with a slight modification of the classical compounds.  Examples include Levonantradol, which was not approved for therapeutic use due to its undesirable side effects.


These synthetic cannabinoids are all on the banned list of the World Anti Doping Agency (WADA). For this reason, they fall outside our research spectrum and are only explained in this overview for reasons of completeness.


Plant cannabinoids, also known as phytocannabinoids, are cannabinoids derived from plants. They are structurally similar to endocannabinoids and have similar pharmacological properties. Both phytocannabinoids and endocannabinoids activate the cannabinoid receptors CB1 and CB2 of the endocannabinoid system. Phytocannabinoids are mainly found in the hemp plant Cannabis sativa and Cannabis indica. However, recent research shows that other plants can also produce phytocannabinoids that act on the endocanabinoid system. The human endocannabinoid system was only discovered with the research of phytocannabinoids. The hemp plant Cannabis Sativa contains more than 85 researched phytocannabinoids from the group of so-called terpene phenols. The best known and most studied are THC (Δ-Tetrahydrocannabinol), the CBD (Cannabidiol). The phytocannabinoids of cannabis have partially opposite effects. There are agonists (substances (ligands) which activate the signal transduction in the corresponding cell by the occupation of a receptor) of the receptors CB1 and CB2, while others express no or only little affinity or are antagonists of the cannabinoid receptors. In addition to the two known phytocannabinoids CBD and THC, CBN, CBG and CBC are also thought to have potential for clinical research. However, these cannabinoids occur in such small amounts in conventional plants that there is still too little data available. An overview of cannabinoids and their effects shows that CBD is clearly the cannabinoid with the most therapeutic and performance-enhancing potential.


The human body can produce cannabinoids itself. Responsible for this is the endocannabinoid system (ECS), which is part of the nervous system. Endocannabinoids are part of the ECS and activate the receptors present in the ECS. Endocannabinoids are believed to play an important role in learning and movement processes. The endocannabinoid system and the endocannabinoids were named after the active substances of the cannabis plant, the cannabinoids. Endocannabinoids are not peptides (molecules made up of amino acids), but derivatives of the non-oxidative metabolism of a fatty acid.  They belong to the family of so-called elicosanoids. Elicosanoids are compounds derived from polyunsaturated fatty acids). One of the most important endocannabinoids is anandamide. Endocannabinoids have an effect on the human psyche and body.